Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 30
Human Site: S296 Identified Species: 44
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S296 Q P K A N A P S F F M A D E L
Chimpanzee Pan troglodytes XP_001136622 741 82148 S296 Q P K A N A P S F F M A D E L
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S296 Q P K A N A P S F F M A D E L
Dog Lupus familis XP_543150 987 105833 S542 Q P K A N A P S F F M A D E L
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 F283 V D S Y H S L F P L E P L P P
Rat Rattus norvegicus XP_002724835 883 95283 S438 Q P K A N A P S F F M A D E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 I300 A Q I D Q A D I P A V P A E V
Chicken Gallus gallus XP_417120 757 83269 S313 Q P K A N A P S F F M A D E L
Frog Xenopus laevis NP_001128699 631 68072 H223 F S Q A L F S H P S M G G P T
Zebra Danio Brachydanio rerio XP_002666687 799 86684 S355 Q P K A N A P S F F M A D E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 A300 V V D G T H P A L H G V S A V
Honey Bee Apis mellifera XP_623553 607 67474 L199 E V D N Y H E L C P L E P I H
Nematode Worm Caenorhab. elegans P34653 632 71182 A224 Q L A Y D T K A D S A I I G D
Sea Urchin Strong. purpuratus XP_796055 760 83393 S315 K R N V N G P S F F M D E E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 L271 E D L T K K N L S I L Q V F P
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 H248 N L Q K K L F H M Q Q L L P N
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 0 100 N.A. 13.3 100 13.3 100 N.A. 6.6 0 6.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 100 N.A. 26.6 100 20 100 N.A. 20 13.3 20 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 50 0 50 0 13 0 7 7 44 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 13 13 7 7 0 7 0 7 0 0 7 44 0 7 % D
% Glu: 13 0 0 0 0 0 7 0 0 0 7 7 7 57 0 % E
% Phe: 7 0 0 0 0 7 7 7 50 50 0 0 0 7 7 % F
% Gly: 0 0 0 7 0 7 0 0 0 0 7 7 7 7 0 % G
% His: 0 0 0 0 7 13 0 13 0 7 0 0 0 0 7 % H
% Ile: 0 0 7 0 0 0 0 7 0 7 0 7 7 7 0 % I
% Lys: 7 0 44 7 13 7 7 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 7 0 7 7 7 13 7 7 13 7 13 0 44 % L
% Met: 0 0 0 0 0 0 0 0 7 0 57 0 0 0 0 % M
% Asn: 7 0 7 7 50 0 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 44 0 0 0 0 57 0 19 7 0 13 7 19 13 % P
% Gln: 50 7 13 0 7 0 0 0 0 7 7 7 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 7 0 0 7 7 50 7 13 0 0 7 0 0 % S
% Thr: 0 0 0 7 7 7 0 0 0 0 0 0 0 0 7 % T
% Val: 13 13 0 7 0 0 0 0 0 0 7 7 7 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _